Prevalence of COVID-19 among Mothers and Infant and Their Factors of Infection Transmission: A Cross-sectional Study
Published: 2022-11-19
Page: 231-239
Issue: 2022 - Volume 5 [Issue 1]
Suryani Manurung *
Department of Nursing, Health Polytechnic, Ministry of Health Jakarta 1, Wijayakusuma Raya Street No. 47-48 Cilandak, South Jakarta-12430, Indonesia.
Anna Sukmawati
Department of Nursing, Health Polytechnic, Ministry of Health Jakarta 1, Wijayakusuma Raya Street No. 47-48 Cilandak, South Jakarta-12430, Indonesia.
*Author to whom correspondence should be addressed.
Abstract
Aims: This study aims to determine the prevalence of newborns infected with COVID-19 and the factors associated with the transmission of COVID-19 infection in newborns.
Study Design: Research method, cross-sectional design, retrospective. The sample consisted of 145 infants, the inclusion criteria were 0-28 days, and the mother was infected with COVID-19.
Place and Duration of Study: The research location is one of the hospitals in DKI Jakarta Selatan. Implementation from March to May 2022.
Methodology: The instrument of observation used the medical records of mothers and babies. Chi-Square and Mann-Whitney data analysis.
Results: The results showed the characteristics of pregnant women infected with COVID-19: the average age of 29.87 years, gestational age of 37 weeks, and gestational age at delivery of 37 weeks. The prevalence of COVID-19 infection in infants born to mothers exposed to COVID-19 at the age of 0 days was 99.3%. 101 (69.7%) delivery by cesarean section, 44 (30.3%) spontaneous delivery. Transmission of COVID-19 to neonates based on transplacental factors was seen from the maternal D dimer value (p-value < 0.05). The relationship between confounding factors that affect the transmission of COVID-19 infection in neonates from pregnant women aged 26-35 years is the gestational age of the mother when infected. Likewise, the confounding factor of gestational age, namely maturity, has an effect on COVID-19 infection in neonates seen from gestational age at delivery.
Conclusion: The prevalence of infants infected with COVID-19 occurs at the age of 0 days, infection transmission is estimated from birth.
Keywords: COVID-19, pregnancy, transmission factors, newborn
How to Cite
Downloads
References
POGI. Revisi-rekomendasi-POGI-utk-bumil-dengan-Covid-19-.pdf [Internet]. IDI2021 [Cited 2022 Jan 1];1–5.
Wu YT, Liu J, Xu JJ, Chen YF, Yang W, Chen Y, et al. Neonatal outcome in 29 pregnant women with COVID-19: A retrospective study in Wuhan, China. PLoS Med. [Internet] 2020 [Cited 2022 Jan 1];17:1–19.
Available:https://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.1003195
Amorita NA, Syahriarti I. Karakteristik ibu hamil dengan covid-19 dan luaran persalinannya di Rumah Sakit Kasih Ibu Surakarta. J. Kesehat. Reproduksi [Internet] 2021 [cited 2022 Feb 5];8:31.
Available:https://jurnal.ugm.ac.id/jkr/article/view/63936
Fitriyani I. Laporan kasus: tiga neonatus yang lahir dari ibu yang terinfeksi COVID-19 di RSUD. Undata Palu dinyatakan positif covid 19, penularan melalui vertikal ibu ke janin atau karena lingkungan. Cerdika J. Ilm. Indones. [Internet] 2021 [cited 2022 Feb 1];1: 543–9.
Available:https://cerdika.publikasiindonesia.id/index.php/cerdika/article/view/85
Vivanti AJ, Vauloup-Fellous C, Prevot S, Zupan V, Suffee C, Do Cao J, et al. Transplacental transmission of SARS-CoV-2 infection. Nat. Commun. [Internet] 2020 [cited 2022 Feb 10];11:1–7.
Available:https://pubmed.ncbi.nlm.nih.gov/32665677/
Tobing SL, Abimanyu B, Radam MRA, Hartoyo E, Haryati, Budinurdjaja P, et al. A Multidiciplinary approach: pelayanan obgyin dalam situasi pandemi Covid19 [Internet]. Kalimanta Selatan: Program Studi Obstetri Ginekologi FK ULM; 2020.
Available: https://repo-dosen.ulm.ac.id/bitstream/handle/123456789/19182/Buku A Multidisciplinary Approach Pelayanan Obsgin dalam situasi Pandemi Covid-19.pdf?sequence=1&isAllowed=y
Nokhostin F, Saffarieh E, Sharami SRY. Investigating the effect of Covid-19 on pregnant women. J. Crit. Rev. [Internet] 2020 [cited 2022 Dec 1];7:1141–5.
Nurdamayanti F, Riafisari AA, Semarang M. Literatur review : komplikasi kehamilan pada ibu hamil yang terinfeksi. Pros. Semin. Nas. UNIMUS [Internet] 2020; 3:703–10.
Available:https://prosiding.unimus.ac.id/index.php/semnas/article/view/733
Carosso A, Cosma S, Borella F, Marozio L. Pre-labor anorectal swab for SARS-CoV-2 in COVID-19 pregnant patients: is it time to think about it? Eur J Obs. Gynecol Reprod Biol [Internet] 2020 [cited 2022 Aug 1];249:98–99.
Available:https://www.https//www.ejog.org/article/S0301-2115(20)30202-5/fulltext
Hadiyanto ML. Gambaran hingga tatalaksana COVID-19 pada anak. Intisari Sains Medis [Internet] 2021 [cited 2022 Aug 1];12:250–5.
Available:https://www.isainsmedis.id/index.php/ism/article/view/947
WHO. Breastfeeding and COVID-19: Scientific brief [Internet]. WHO2020 [cited 2021 Aug 1];1–3.
Available:https://www.who.int/publications/i/item/WHO-2019-nCoV-Sci_Brief-Breastfeeding-2020.1
Lee PI, Hu YL, Chen PY, Huang YC, Hsueh PR. Are children less susceptible to COVID-19? J Microbiol Immunol Infect [Internet] 2020 [cited 2021 Oct 1];53:371–2.
Available:https://pubmed.ncbi.nlm.nih.gov/32147409/
Yuki K, Fujiogi M, Koutsogiannaki S. COVID-19 pathophysiology: A review. Clin Immunol [Internet] 2020 [cited 2021 Oct 1];215:1–8.
Available:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7169933/pdf/main.pdf
Chen H, Guo J, Wan C, Luo F, Yu X, Wei Zhang, Jiafu Li DZ, et al. Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records. Lancet [Internet] 2020 [cited 2021 Oct 1];395:809–815.
Available:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7159281/
Widiyanto A, Atmojo JT, PH L, Fajriah AS, Putri SI, Nahak M, et al. Meta analisis hubungan COVID-19 dengan persalinan matur. J. keperawatan [Internet] 2021 [cited 2021 Jan 10];13:791–8.
Available:https://journal.stikeskendal.ac.id/index.php/Keperawatan/article/view/1772
Saadaoui M, Kumar M, Khodor S Al. COVID-19 infection during pregnancy: Risk of vertical transmission, fetal, and neonatal outcomes. J Pers Med [Internet] 2021 [cited 2022 Apr 10];11:483.
Available:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8227688/
Koumoutsea EV, Vivanti AJ, Shehata N, Benachi A, Le A, Celine G, et al. COVID-19 and acute coagulopathy in pregnancy. J Thromb Haemost [Internet] 2020 [cited 2022 Jun 1];19:1648–52.
Available:https://pubmed.ncbi.nlm.nih.gov/32302459/
Hedengran KK, Andersen MR, Stender S, Szecsi PB. Large D-Dimer fluctuation in normal pregnancy: A Longitudinal cohort study of 4,117 samples from 714 healthy Danish women. Obstet. Gynecol. Int. [Internet] 2016 [cited 2020 Jun 1];2016: 1–7
Available:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4852125/pdf/OGI2016-3561675.pdf
Chen D, Yang H, Cao Y, Cheng W, Duan T, Fan C, et al. Expert consensus for managing pregnant women and neonates born to mothers with suspected or confirmed novel coronavirus (COVID-19) infection. Int J Gynaecol Obs. [Internet] 2020 [cited 2021 Jun 1];149: 130–6.
Available:https://pubmed.ncbi.nlm.nih.gov/32196655/
Mazur-Bialy AI, Kołomańska-Bogucka D, Tim S, Opławski M. Pregnancy and childbirth in the COVID-19 era-the course of disease and maternal- fetal transmission. J Clin Med [Internet] 2020 [cited 2022 Jun 1];9: 3749.